Tran Laboratory

NINI TRAN, D.D.S., Ph.D.

Assistant Professor

Tran laboratory focuses on diagnostics and therapeutics of early childhood caries related to microbiome and host susceptibility. The primary goal is to examining the role of Streptococcus mutans and the oral microbial communities in children’s susceptibility to early childhood caries. The Tran laboratory also conduct integrated clinical and translational research to test innovations and products in dental and oral health.

Publications

Omics and interspecies interaction

Bhumika Shokeen, Marcia Dalila Botelho Dinis, Farnoosh Haghighi, Nini Chaichanasakul Tran, Renate Lux

Periodontology 2000, vol. 85(1), 2021, pp. 101-111

Oral colonization of Candida albicans and Streptococcus mutans in children with or without fixed orthodontic appliances: A pilot study

Fang Yang, Márcia Dinis, Farnoosh Haghighi, Xuesong He, Wenyuan Shi, Nini C. Tran

Journal of Dental Sciences, 2021

Deep metagenomics examines the oral microbiome during dental caries, revealing novel taxa and co-occurrences with host molecules

Jonathon L Baker, James T Morton, Marcia Dinis, Ruth Alvarez, Nini C Tran, Rob Knight, Anna Edlund

Genome Research, vol. 31(1), 2021, pp. 64-74

Pilot study on selective antimicrobial effect of a halitosis mouthrinse: monospecies and saliva-derived microbiome in an in vitro model system

Márcia Botelho Dinis, Melissa Agnello, Xuesong He, Wenyuan Shi, Nini Chaichanasakul Tran

Journal of Oral Microbiology, vol. 13(1), 2021

Effectiveness of the GumChucks flossing system compared to string floss for interdental plaque removal in children: a randomized clinical trial

Joshua Lin, Márcia Dinis, Chi-Hong Tseng, Melissa Agnello, Xuesong He, Daniela R Silva, Nini C Tran

Scientific Reports, vol. 10(1), 2020, pp. 1-8

Identification of the bacterial biosynthetic gene clusters of the oral microbiome illuminates the unexplored social language of bacteria during health and disease

Gajender Aleti, Jonathon L Baker, Xiaoyu Tang, Ruth Alvarez, Márcia Dinis, Nini C Tran, Alexey V Melnik, Cuncong Zhong, Madeleine Ernst, Pieter C Dorrestein, Anna Edlund

MBio, vol. 4(16), 2019, pp. e00321-19

Microbiome associated with severe caries in Canadian first nations children

M Agnello, J Marques, L Cen, B Mittermuller, A Huang, N Chaichanasakul Tran, W Shi, X He, RJ Schroth

Journal of Dental Research, vol. 96(12), 2017, pp. 1378-1385

Arginine Improves pH Homeostasis via Metabolism and Microbiome Modulation

M Agnello, L Cen, Tran NC, Shi W, McLean JS, He X

Journal of Dental Research, vol. 96(8), 2017, pp. 924-930

Diverse osteoclastogenesis of bone marrow from mandible versus long bone

Thawinee Chaichanasakul, Benjamin Kang, Olga Bezouglaia, Tara L Aghaloo, Sotirios Tetradis

Journal of Periodontology, vol. 85(6), 2014, pp. 829-836

Periapical disease and bisphosphonates induce osteonecrosis of the jaws in mice

Ben Kang, Simon Cheong, Thawinee Chaichanasakul, Olga Bezouglaia, Elisa Atti, Sarah M Dry, Flavia Q Pirih, Tara L Aghaloo, Sotirios Tetradis